| 赵晶晶,张汀汀,刘晓华,孙纪新,刘玉环,岳福娟,张帆,曹亚景.睡眠时间与成年人代谢综合征相关性的Meta分析[J].Chinese journal of Epidemiology,2020,41(8):1272-1279 |
| 睡眠时间与成年人代谢综合征相关性的Meta分析 |
| A Meta-analysis on the association between sleep duration and metabolic syndrome in adults |
| Received:January 06, 2020 |
| DOI：10.3760/cma.j.cn112338-20200106-00013 |
| KeyWord: 睡眠时间 代谢综合征 Meta分析 观察性研究 |
| English Key Word: Sleep duration Metabolic syndrome Meta-analysis Observational study |
| FundProject:河北省医学科学研究课题（20200697） |
| Author Name | Affiliation | E-mail | | Zhao Jingjing | Hebei Provincial Center for Disease Control and Prevention of Chronic Non-communicable Diseases, Shijiazhuang 050021, China | | | Zhang Tingting | Hebei Provincial Center for Disease Control and Prevention of Parasite Control, Shijiazhuang 050021, China | | | Liu Xiaohua | Beijing Vista Medical Center, Beijing 100020, China | | | Sun Jixin | Hebei Provincial Center for Disease Control and Prevention of Chronic Non-communicable Diseases, Shijiazhuang 050021, China | | | Liu Yuhuan | Hebei Provincial Center for Disease Control and Prevention of Chronic Non-communicable Diseases, Shijiazhuang 050021, China | | | Yue Fujuan | Hebei Provincial Center for Disease Control and Prevention of Chronic Non-communicable Diseases, Shijiazhuang 050021, China | | | Zhang Fan | Hebei Provincial Center for Disease Control and Prevention of Chronic Non-communicable Diseases, Shijiazhuang 050021, China | | | Cao Yajing | Hebei Provincial Center for Disease Control and Prevention of Chronic Non-communicable Diseases, Shijiazhuang 050021, China | 191419688@qq.com |
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| Abstract: |
| 目的 对睡眠时间与成年人MS之间的关系进行定量评估，以期为MS的防治提供科学依据。方法 检索中英文数据库，纳入2019年10月以前已发表的相关文献。采用Stata 11.0软件对纳入的文献进行Meta分析。结果 最终纳入38篇文献，包含研究对象共计656 319例，其中MS患者共150 638例。睡眠时间与MS存在“U”形关联，短睡眠时间者患MS风险是正常睡眠者的1.11倍（95% CI：1.07～1.16），长睡眠时间者患MS风险是正常睡眠者的1.10倍（95% CI：1.03～1.18）。亚组分析显示，横断面研究中，相对于正常睡眠时间组，短睡眠时间使男性、<60岁人群、亚洲人及白种人患MS风险分别增加6%、14%、9%和24%，长睡眠时间使女性和<60岁人群患MS风险分别增加13%和19%。队列研究中观察到亚洲人短睡眠时间与MS呈正相关（RR=1.10，95% CI：1.07～1.13），白种人长睡眠时间与MS呈正相关（RR=1.56，95% CI：1.08～2.26）。结论 MS与长睡眠时间和短睡眠时间之间均存在关联。睡眠是可以改变的行为习惯，因此通过干预睡眠以降低MS患病风险具有重要的公共卫生意义。 |
| English Abstract: |
| Objective To quantitatively evaluate the relationship between sleep duration and metabolic syndrome in adults in order to set up programs on prevention and treatment of metabolic syndrome in this population. Methods Relevant studies were identified by systematically searching databases before October 2019. All statistical analyses were under the use of Stata 11.0. Results A total of 656 319 participants including 150 638 cases with metabolic syndrome were involved in thes 38 articles. A U-shaped relationship between sleep duration and metabolic syndrome was noticed. For short and long sleep duration, the OR=1.11 (95%CI:1.07-1.16) and 1.10 (95%CI:1.03-1.18), respectively. Subgroup analyses on cross-sectional studies revealed that factors as men, aged under 60 years, being Asians or Caucasians would increase the risk of metabolic syndrome by 6%, 14%, 9%, and 24%, respectively for those with short sleep duration. Factors as aged 60 years and above, being black and with long sleep duration, would increase the risks of metabolic syndrome by 13% and 19%, respectively in women. In subgroup analyses on cohort studies, positive correlation between short sleep duration and metabolic syndrome was observed in both Asian (RR=1.10, 95%CI:1.07-1.13) and in Caucasians (RR=1.56, 95%CI:1.08-2.26) populations. Conclusions Results of this study revealed an association between metabolic syndrome and the duration of sleep. We understand that sleep is a behavior that can be changed step by step, through adequate intervention programs, to reduce the risk of metabolic syndrome which has become an important public health issue. |
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