| 王盛书,杨姗姗,贾王平,曹文哲,韩珂,李靖,台朋岗,寇福银,赵亚力,朱乔,甯超学,刘淼,何耀.海南百岁老人血脂水平及分布特征[J].Chinese journal of Epidemiology,2021,42(1):80-87 |
| 海南百岁老人血脂水平及分布特征 |
| Distribution characteristics of blood lipid profile in Hainan centenarians |
| Received:April 24, 2020 |
| DOI：10.3760/cma.j.cn112338-20200424-00636 |
| KeyWord: 血脂谱 百岁老人 海南 流行特征 |
| English Key Word: Lipid profile Centenarian Hainan Epidemiological characteristics |
| FundProject:国家自然科学基金（81703285，81773502，81703308）；北京市科技新星计划（Z181100006218085）；解放军总医院优秀青年项目（2018-YQPY-003）；解放军总医院“3+1”新秀人才项目；国家老年疾病临床医学研究中心开放课题（NCRCG-PLAGH-2017017）；解放军总医院医疗大数据研发项目（2018MBD-029，MBD2018030）；国家重点研发计划（2016YFC1303603，2018YFC2000400）；国家科技资源共享服务平台计划（YCZYPT［2018］07） |
| Author Name | Affiliation | E-mail | | Wang Shengshu | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Yang Shanshan | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Jia Wangping | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Cao Wenzhe | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Han Ke | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Li Jing | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China
Health Service Department, the Fifth Medical Center of Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Tai Penggang | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Kou Fuyin | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Zhao Yali | Central Laboratory of Hainan Hospital, Chinese People's Liberation Army General Hospital, Sanya 572013, China | | | Zhu Qiao | Central Laboratory of Hainan Hospital, Chinese People's Liberation Army General Hospital, Sanya 572013, China | | | Ning Chaoxue | Central Laboratory of Hainan Hospital, Chinese People's Liberation Army General Hospital, Sanya 572013, China | | | Liu Miao | Department of Statistics and Epidemiology, Graduate School, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | He Yao | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China | yhe301@sina.com |
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| Abstract: |
| 目的 探讨我国海南百岁老人血脂谱水平流行分布特征及血脂异常影响因素，为百岁老人血脂相关研究提供基础数据。方法 数据来自中国海南百岁老人队列研究2014-2016年基线数据集，共纳入1 002例百岁老人，根据《中国成人血脂异常防治指南（2016年修订版）》中国成人血脂异常诊断标准，描述血脂谱流行分布及不同临床分类的血脂异常患病率差异，分析血脂异常与主要影响因素的关联性。结果 我国海南百岁老人TC、TG、LDL-C和HDL-C的中位数水平分别为4.60、1.05、2.77和1.41 mmol/L，女性均高于男性。TC、TG和LDL-C随BMI升高显著升高，HDL-C随着BMI升高下降。总体血脂异常患病率为19.1%。吸烟、BMI升高和地区是血脂异常的主要影响因素。结论 我国海南百岁老人血脂谱水平较国内外相关研究人群处于较低水平，女性血脂谱水平显著高于男性。 |
| English Abstract: |
| Objective To explore the prevalence of lipid profile and the influencing factors of dyslipidemia in centenarians in Hainan province, and provide basic data for the study of the lipid profile in centenarians. Methods The data of this study were from the baseline data of China Hainan Centenarian Cohort Study from June 2014 to December 2016. A total of 1 002 centenarians were recruited. According to the guidelines for the prevention and treatment of dyslipidemia in Chinese adults in 2016, the prevalence of lipid profile were described and the prevalence of dyslipidemia with different clinical classifications were compared, and the main influencing factors were analyzed. Results The median levels of TC, TG, LDL-C and HDL-C were 4.60 mmol/L, 1.05 mmol/L, 2.77 mmol/L and 1.41 mmol/L, respectively, in centenarians in Hainan. Blood lipid profile level was higher in females than in males. With the increase of BMI, TC, TG and LDL-C increased significantly, while HDL-C decreased significantly. The total prevalence of dyslipidemia was 19.1%. Smoking, BMI and area distribution were the main influencing factors of dyslipidemia. Conclusion The prevalence of dyslipidemia in centenarians in Hainan was at a low level compared with other countries, and the blood lipid profile level was higher in females than in males. |
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