| 杨姗姗,王盛书,贾王平,韩珂,台朋岗,寇福银,李靖,曹文哲,赵亚力,朱乔,甯超学,刘淼,何耀.海南百岁老人中肥胖相关指标与抑郁症状风险的关联研究[J].Chinese journal of Epidemiology,2021,42(1):113-120 |
| 海南百岁老人中肥胖相关指标与抑郁症状风险的关联研究 |
| Relationship between obesity related anthropometric indicators and depression risk in Hainan centenarians |
| Received:April 25, 2020 |
| DOI：10.3760/cma.j.cn112338-20200425-00644 |
| KeyWord: 百岁老人 小腿围 腰围小腿围比值 抑郁症状风险 人体测量 |
| English Key Word: Centenarian Calf circumference Waist-calf circumference ratio Depression risk Anthropometric measuring |
| FundProject:国家自然科学基金（81773502，81703308，81703285）；国家重点研发计划（2016YFC1303603，2018YFC2000400）；北京市自然科学基金（7174350）；北京市科技新星计划（Z181100006218085）；肾脏病国家重点实验室开放课题（KF-01-115）；国家老年疾病临床医学研究中心开放课题（NCRCG-PLAGH-2017017）；国家科技资源共享服务平台计划（YCZYPT［2018］07）；解放军总医院医疗大数据研发项目（MBD2018030） |
| Author Name | Affiliation | E-mail | | Yang Shanshan | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China
Department of Disease Prevention and Control, the First Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Wang Shengshu | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Jia Wangping | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Han Ke | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Tai Penggang | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Kou Fuyin | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Li Jing | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China
Health Service Department, the Fifth Medical Center of Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Cao Wenzhe | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | Zhao Yali | Central Laboratory of Hainan Hospital, Chinese People's Liberation Army General Hospital, Sanya 572013, China | | | Zhu Qiao | Central Laboratory of Hainan Hospital, Chinese People's Liberation Army General Hospital, Sanya 572013, China | | | Ning Chaoxue | Central Laboratory of Hainan Hospital, Chinese People's Liberation Army General Hospital, Sanya 572013, China | | | Liu Miao | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China
Department of Statistics and Epidemiology, Graduate School, Chinese People's Liberation Army General Hospital, Beijing 100853, China | | | He Yao | Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China | yhe301@sina.com |
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| Abstract: |
| 目的 分析百岁老人中腰围、BMI、腰臀比、腰高比、小腿围和腰围小腿围比值（WCR）与其抑郁症状风险间的关联。方法 纳入全样本调查的海南百岁老人共1 002人。使用GDS-15进行抑郁症状相关风险的调查，使用多元线性回归和logistic回归分析各人体测量指标与抑郁症状风险间的关联强度。结果 校正人口学特征（性别、年龄、民族、婚姻状况、文化程度和居住类型）以及生活方式（吸烟和饮酒）相关变量后，总人群中BMI、腰围、腰臀比、腰高比、小腿围和WCR与GDS-15关联的标准β值分别为-0.069、-0.032、0.009、-0.009、-0.099和0.060，其中关于上述β值的检验P值中BMI和小腿围<0.05。随小腿围增加，百岁老人的抑郁症状风险随之降低，OR=0.94（95%CI：0.90~0.98）。而logistic回归分析中显示，随着小腿围的减少和WCR的增加，抑郁症状的风险逐步增加，趋势P值分别为0.038和0.042。结论 百岁老人中，中心肥胖（腰围、WCR）与外周肥胖（小腿围）对于抑郁症状具有不同关联，百岁女性中小腿围增加是其抑郁症状风险的保护因素，应关注小腿围较低的老年女性的心理健康问题。 |
| English Abstract: |
| Objective To analyze the association of waist circumference, BMI, waist-hip ratio, waist-height ratio, calf circumference and waist-calf circumference ratio (WCR) with depression risk in centenarians in Hainan province. Methods A total of 1 002 centenarians in Hainan were selected by cluster sampling. GDS-15 was used to investigate the depression. Multivariate linear regression and logistic regression analyses were conducted to evaluate the correlation between anthropometric indicators and depression risk. Restricted cubic spline was used to analyze and visualize the linear relationship. Results After adjusting demographic characteristics (gender, age, ethnic group, marital status, educational level and type of residence) and lifestyle (smoking and drinking), the standard β of BMI, WC, WHR, WHtR, calf circumference and WCR associated with GDS-15 were -0.069, -0.032,0.009, -0.009, -0.099 and 0.060, respectively, and the P values of BMI and calf circumference were <0.05. With the increase of calf circumference, the risk of depression decreased, OR value was 0.94 (95% CI:0.90-0.98), and after adjustment, the results were still significant. Classified variable analysis indicated with the decrease of calf circumference and the increase of WCR, the risk of depression increased gradually, the trend P values were 0.038 and 0.042, respectively. Conclusion Central obesity (waist circumference and WCR) and periphery obesity (calf circumference) have differed effects on depression in centenarians, and increased calf circumference is a protective factor for depression in female centenarians, attention should be paid to the mental health of the elderly women with lower calf circumference. |
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