| 徐冰,赫晓霞,任雅楠,王俊,邢文革.HCV核酸检测用于临床诊断的研究进展[J].Chinese journal of Epidemiology,2021,42(1):153-159 |
| HCV核酸检测用于临床诊断的研究进展 |
| Advances in studies of HCV nucleic acid testing for clinical diagnosis |
| Received:March 17, 2020 |
| DOI：10.3760/cma.j.cn112338-20200317-00371 |
| KeyWord: HCV 核酸检测 检测策略 |
| English Key Word: HCV Nucleic Acid Testing Testing Strategy |
| FundProject: |
| Author Name | Affiliation | E-mail | | Xu Bing | National HIV/AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention. Beijing 102206, China | | | He Xiaoxia | Beijing Engineering Technology Research Centre of Gene Sequencing and Gene Function Analysis, Beijing Engineering Research Center of Food Safety Analysis, Beijing Center for Physical & Chemical Analysis, Beijing 100089, China | | | Ren Yanan | National HIV/AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention. Beijing 102206, China | | | Wang Jun | National HIV/AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention. Beijing 102206, China | | | Xing Wenge | National HIV/AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention. Beijing 102206, China | xingwenge@sina.com |
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| Abstract: |
| HCV感染呈全球流行，发病隐匿。实验室检测是临床诊断的主要依据，其检测方法主要为抗体检测和核酸检测。为实现对HCV感染的早发现、早诊断，选择最佳检测方法和诊断策略尤为重要。本文从HCV核酸检测方法，试剂的性能评价以及目前的HCV检测策略进行综述。 |
| English Abstract: |
| HCV infection is of global concern with the characteristic of insidious onset. Laboratory testing stands indispensably for clinical diagnosis with antibody assay and nucleic acid testing the main methods being adopted. For early detection and diagnosis of HCV infection, it is important to choose the best detection method and diagnostic strategy. This paper reviews the HCV nucleic acid testing methods, as well as performance evaluation of reagents and current strategies. |
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