| 陈希,邹启,甄若楠,谢朝军,黄炯今,刘览,黄勇,马钰,李科,汪慧,陈宗遒,刘于飞,袁俊.构建大规模人群新型冠状病毒核酸筛查指标体系研究[J].Chinese journal of Epidemiology,2021,42(8):1353-1359 |
| 构建大规模人群新型冠状病毒核酸筛查指标体系研究 |
| Establishment of index system for population based SARS-CoV-2 nucleic acid screening |
| Received:February 09, 2021 |
| DOI：10.3760/cma.j.cn112338-20210209-00106 |
| KeyWord: 德尔菲法 新型冠状病毒 核酸筛查 指标体系 |
| English Key Word: Delphi method SARS-CoV-2 Nucleic acid screening Index system |
| FundProject:广州市医学重点学科（2021-2023-11）；广州市重点实验室基础计划（202102100001）；广州市卫生计生科技一般引导项目（20181A011050） |
| Author Name | Affiliation | E-mail | | Chen Xi | Institute of Public Health, Guangzhou Medical University, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China | | | Zou Qi | School of Public Health, Guangzhou Medical University, Guangzhou 511436, China | | | Zhen Ruonan | Institute of Public Health, Guangzhou Medical University, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China | | | Xie Zhaojun | Institute of Public Health, Guangzhou Medical University, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China | | | Huang Jiongjin | School of Public Health, Southern Medical University, Guangzhou 510515, China | | | Liu Lan | Institute of Public Health, Guangzhou Medical University, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China | | | Huang Yong | Institute of Public Health, Guangzhou Medical University, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China | | | Ma Yu | Institute of Public Health, Guangzhou Medical University, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China | | | Li Ke | Institute of Public Health, Guangzhou Medical University, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China | | | Wang Hui | Institute of Public Health, Guangzhou Medical University, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China | | | Chen Zongqiu | Institute of Public Health, Guangzhou Medical University, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China | | | Liu Yufei | Institute of Public Health, Guangzhou Medical University, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China | | | Yuan Jun | Institute of Public Health, Guangzhou Medical University, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China | yuanjuncom@163.com |
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| Abstract: |
| 目的 建立适用于大规模人群新型冠状病毒（新冠病毒）核酸筛查时，科学确定筛查范围的指标体系。方法 采用文献检索和头脑风暴法，拟定大规模人群新冠病毒核酸筛查指标体系初始框架和指标，通过层次分析法及Delphi法结合的方式，对全国21名专家进行两轮咨询，确定大规模人群新冠病毒核酸筛查指标体系及权重。结果 两轮咨询的专家积极指数均为100%，权威系数（Cr）分别为0.88±0.08、0.89±0.07，变异系数（CV）范围（0.08，0.24）、（0.09，0.25）；Kendall's W协调系数分别为0.34、0.22，差异有统计学意义（χ2=97.02、249.90，P<0.05）。最终确立了包括4个一级指标、11个二级指标、58个三级指标的大规模人群新冠病毒核酸筛查指标体系，并确定了各指标权重。结论 初步建立了大规模人群新冠病毒核酸筛查指标体系，对卫生行政部门科学和精准地确定大规模人群筛查范围时提供参考依据。 |
| English Abstract: |
| Objective To establish an index system of population based SARS-CoV-2 nucleic acid screening, and provide reference to determine the screening coverage appropriately.Methods The literature review and brain storming sessions were used to develop the basic frame and index system of population based SARS-CoV-2 nucleic acid screening. Based on Delphi method and Analytic Hierarchy Process, 21 domestic experts were selected for two rounds of consultation to determine the index system of population based SARS-CoV-2 nucleic acid screening and its weight.Results The positive indexes of experts in two rounds of consultations were both 100%. The experts' authority coefficients (Cr) were 0.88±0.08 and 0.89±0.07, respectively. And the range of coefficient of variation (CV) were (0.08, 0.24), (0.09, 0.25). The Kendall's W coordination coefficients were 0.34 and 0.22 respectively, which were statistically significant. The index system of population based SARS-CoV-2 nucleic acid screening was established, which had 4 first-level indexes, 11 second-level indexes and 58 third-level indexes. Besides, the weight of each index was determined.Conclusion The index system of population based SARS-CoV-2 nucleic acid screening has been established, which can provide scientific reference for the health administration to determine the coverage of population based SARS-CoV-2 nucleic acid screening when local COVID-19 epidemic occurs. |
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