男男性行为者对HIV非职业暴露后预防的认知及相关因素分析

杨雪; 李杰; 王博; 韩晶; 王辉; 宋兵; 刘俊; 王丽艳; 庞琳; 张广; 汤后林; 刘童童

Abstract

杨雪,李杰,王博,韩晶,王辉,宋兵,刘俊,王丽艳,庞琳,张广,汤后林,刘童童.男男性行为者对HIV非职业暴露后预防的认知及相关因素分析[J].Chinese journal of Epidemiology,2021,42(10):1840-1845

男男性行为者对HIV非职业暴露后预防的认知及相关因素分析

Cognition and related factors on the use of HIV non-occupational post-exposure prevention among men who have sex with men

Received:April 20, 2021

DOI：10.3760/cma.j.cn112338-20210420-00329

KeyWord: 艾滋病病毒男男性行为者非职业暴露后预防相关因素

English Key Word: HIV Men who have sex with men Non-occupational post-exposure prophylaxis Related factors

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Author Name	Affiliation	E-mail
Yang Xue	National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Li Jie	Chinese Association of STD and AIDS Prevention and Control, Beijing 100050, China
Wang Bo	Beijing Youan Hospital, Capital Medical University, Beijing 100069, China
Han Jing	Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
Wang Hui	The Third People's Hospital of Shenzhen, Shenzhen 518112, China
Song Bing	The Fifth Medical Center of General Hospital of Chinese People's Liberation Army, Beijing 100039, China
Liu Jun	The Third People's Hospital of Kunming, Kunming 650041, China
Wang Liyan	People's Medical Investment Management Limited Company, People's Medical Publishing House, Beijing 100021, China
Pang Lin	National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Zhang Guang	National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Tang Houlin	National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China	tanghl@chinaaids.cn
Liu Tongtong	Chinese Health Education Center, Beijing 100011, China	15160188@qq.com

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Abstract:

目的了解MSM对HIV非职业暴露后预防（nPEP）的认知情况，以及使用nPEP的相关因素。方法 2019年3月15日至4月14日，采用滚雪球抽样方法，分别在北京市、深圳市和昆明市MSM社会组织招募年龄≥18岁男性、最近3个月发生过男男性行为、听说过HIV nPEP等符合条件的研究对象，通过“i卫士”收集人口学、行为学特征、nPEP基本知识及其咨询和使用情况。采用logistic回归模型对是否使用nPEP的相关因素进行分析。结果共调查1 809人，nPEP基本知识知晓率为39.8%（720/1 809），33.4%（605/1 809）咨询过nPEP，15.0%（271/1 809）使用过nPEP。多因素logistic回归分析结果显示，研究对象使用nPEP的相关因素包括最近3个月与男性HIV感染者发生过性行为（OR=2.58，95%CI：1.64~4.07）、最近1年HIV检测次数≥2次（OR=2.47，95%CI：1.28~5.11）、nPEP基本知识知晓（OR=0.70，95%CI：0.49~0.99）、咨询过nPEP（OR=70.98，95%CI：40.51~136.83）。结论 MSM对nPEP认知不足，应加强MSM的nPEP相关宣传教育，促进MSM发生HIV暴露后尽快使用nPEP。

English Abstract:

Objective To understand the cognition and related factors on the use of HIV non-occupational post-exposure prophylaxis (nPEP) among men who have sex with men (MSM).Methods The snowballing method was applied to recruit research subjects who were ≥ 18 years old, had sex with men in the past three months, and were aware of nPEP in MSM groups in Beijing, Shenzhen, and Kunming from March 15 to April 14, 2019. Data on social demographics, behavioral characteristics, basic knowledge of nPEP, consultation, and using nPEP were collected through "i guardian Platform". The logistic regression model was used to analyze the related factors affecting the use of nPEP. Results Among 1 809 investigated, 39.8% (720 persons) were aware of the basic knowledge of nPEP, 33.4% (605 persons) had consulted nPEP, and 15.0% (271 persons) had used nPEP. In addition, multivariate logistic regression analysis showed that factors as whether to have sex with men infected with HIV in the last three months (OR=2.58, 95%CI: 1.64-4.07), the frequency of HIV testing in the past year (OR=2.47, 95%CI:1.28-5.11), nPEP knowledge awareness (OR=0.70, 95%CI:0.49-0.99), whether to consult nPEP (OR=70.98, 95%CI:40.51-136.83) were related to the use of nPEP. Conclusions MSM still have poor cognition of nPEP. It is necessary to strengthen the publicity and education of nPEP in MSM and promote the use of nPEP after HIV exposure as soon as possible.

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