男男性行为人群HIV/AIDS性伴感染状况和溯源效率相关因素研究

洪航; 张丹丹; 姜海波; 史宏博; 谭诗文; 顾文珍; 许国章

Abstract

洪航,张丹丹,姜海波,史宏博,谭诗文,顾文珍,许国章.男男性行为人群HIV/AIDS性伴感染状况和溯源效率相关因素研究[J].Chinese journal of Epidemiology,2021,42(12):2100-2105

男男性行为人群HIV/AIDS性伴感染状况和溯源效率相关因素研究

HIV infection and related factors of traceability efficiency among sex partners of HIV positive men who have sex with men

Received:August 11, 2021

DOI：10.3760/cma.j.cn112338-20210811-00632

KeyWord: 艾滋病男男性行为人群性伴检测溯源

English Key Word: AIDS Men who have sex with men Sex partner testing Tracing

FundProject:浙江省自然科学基金（LQ20H260005）；宁波市自然科学基金（2019A610380）；浙江省医学重点学科（07-013）；宁波市市级医疗卫生品牌学科（PPXK2018-10）；国家科技重大专项（2017ZX10201101）

Author Name	Affiliation	E-mail
Hong Hang	Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China
Zhang Dandan	Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China
Jiang Haibo	Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China
Shi Hongbo	Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China
Tan Shiwen	Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China
Gu Wenzhen	Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China
Xu Guozhang	Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China	xugz@nbcdc.org.cn

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Abstract:

目的了解MSM HIV/AIDS的性伴感染状况和溯源效率的相关因素。方法采用横断面调查方法，2018-2020年在宁波市对MSM HIV/AIDS开展性伴调查和HIV检测，并用限制性抗原亲和力酶联免疫法判定是否新发感染。分类资料采用χ²检验，采用多因素logistic回归分析溯源效率的相关因素。结果共调查374例新确证MSM HIV/AIDS，动员479例性伴进行调查和HIV检测，性伴HIV阳性率为15.7%（75/479，95%CI：12.4%~18.9%），其中新发感染者性伴HIV阳性率为31.8%（21/66，95%CI：20.3%~43.4%）。新发感染者的性伴HIV阳性者中新发现阳性性伴的比例（76.2%）高于长期感染者（48.1%），差异有统计学意义（P=0.028）。多因素logistic回归分析结果显示，36~45岁年龄组（与18~25岁年龄组相比，OR=3.973，95%CI：1.364~11.569）、HIV主动检测（与HIV被动检测相比，OR=1.896，95%CI：1.083~3.319）、新发感染者（与长期感染者相比，OR=3.733，95%CI：1.844~7.556）的溯源效率更高。结论 MSM HIV/AIDS性伴HIV阳性率高，其中新发感染者和HIV主动检测发现的感染者性伴溯源效率较高。建议加强MSM HIV/AIDS溯源调查，重点关注艾滋病自愿咨询与检测门诊新确证的MSM HIV/AIDS。

English Abstract:

Objective To investigate the situation related to HIV infection and influencing factors of traceability efficiency among sex partners of HIV positive men who have sex with men (MSM). Methods A cross-sectional survey was conducted to investigate the traceability among sex partners of HIV-positive MSM in Ningbo from 2018 to 2020. Limiting-antigen avidity enzyme immunoassay determined recent HIV infection. The classified data was evaluated by chi-square test, and factors of traceability efficiency were analyzed by multivariate logistic regression. Results A total of 374 newly confirmed HIV-positive MSM were recruited to participate in the HIV test in Ningbo from 2018 to 2020.HIV positive rate of sex partner was 15.7% (75/479,95%CI:12.4%-18.9%). HIV positive rates of sex partner of recent HIV infection MSM was 31.8% (21/66,95%CI:20.3%-43.4%). The proportion of newly confirmed HIV-positive sex partners of recent HIV infection MSM (76.2%) was higher than that of long-term HIV infection MSM (48.1%). The difference was statistically significant (P=0.028). Results from the multivariate logistic regression analysis showed that HIV traceability efficiency was higher in the following subpopulations as; HIV positive MSM who were 36-45 years old (compared with 18-25 years old, OR=3.973,95%CI:1.364-11.569), HIV active detection (compared with HIV passive detection, OR=1.896, 95%CI:1.083-3.319), recent HIV infection MSM (compared with long-term HIV infection MSM, OR=3.733, 95%CI:1.844-7.556). Conclusions HIV positive rate among partners of HIV positive MSM was very high. The traceability efficiency, which was recent HIV infection MSM and HIV active detection, was high. It is suggested to strengthen the traceability and focus on the newly confirmed HIV-positive MSM in VCT clinics.

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