Abstract
王巍巍,周庆欣,马蕾,冯世豪,杨智荣,孙凤,詹思延.环境暴露对健康影响的非随机化研究偏倚评价工具ROBINS-E介绍[J].Chinese journal of Epidemiology,2022,43(1):98-104
环境暴露对健康影响的非随机化研究偏倚评价工具ROBINS-E介绍
Introduction of a tool to assess Risk of Bias in Non-randomized Studies-of Environmental Exposure (ROBINS-E)
Received:November 12, 2020  
DOI:10.3760/cma.j.cn112338-20201112-01324
KeyWord: 偏倚风险  评价工具  非随机化研究  环境暴露  系统综述
English Key Word: Risk of bias  Tool for assessment  Non-randomized studies  Environmental exposure  Systematic review
FundProject:国家自然科学基金(72074011);北京市属医院科研培育项目(PX2019071)
Author NameAffiliationE-mail
Wang Weiwei The National Clinical Research Center for Mental Disorders &
Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China 
 
Zhou Qingxin Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Center of Evidence-based Medicine and Clinical Research, Peking University, Beijing 100191, China 
 
Ma Lei Department of Psychiatry, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China  
Feng Shihao School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China  
Yang Zhirong Primary Care Unit, School of Clinical Medicine, University of Cambridge, Cambridge CB1 8RN, UK  
Sun Feng Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Center of Evidence-based Medicine and Clinical Research, Peking University, Beijing 100191, China 
sunfeng@bjmu.edu.cn 
Zhan Siyan Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Center of Evidence-based Medicine and Clinical Research, Peking University, Beijing 100191, China
Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing 100191, China 
 
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Abstract:
      针对非随机化环境暴露研究Cochrane偏倚评估工具ROBINS-E的主要内容进行详细介绍,并举例说明ROBINS-E的使用方法和注意事项。ROBINS-E针对非随机化暴露研究(non-randomized studies of exposures,NRSE)的特点,设置了相应的评估领域和信号问题,为将NRSE纳入到系统综述,在GRADE框架下进行证据整合提供偏倚风险信息。
English Abstract:
      This paper summaries the Risk of Bias in Non-randomized Studies-of Environmental Exposure (ROBINS-E), a tool for evaluating risk of bias about non-randomized studies of exposures (NRSE), and introduces the application of ROBINS-E in a published NRSE. According to the characteristics of NRSE, evaluation fields and signaling questions were designed in ROBINS-E to provide essential information about risk of bias for NRSE included in systematic reviews and GRADE. ROBINS-E is the tool in assessment of risk of bias in observational studies and quasi-randomized studies. Although the tool has been used in practice to some extent, but it still needs further improvement. Attention should be paid to its update and progress.
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