| 王巍巍,周庆欣,马蕾,冯世豪,杨智荣,孙凤,詹思延.环境暴露对健康影响的非随机化研究偏倚评价工具ROBINS-E介绍[J].Chinese journal of Epidemiology,2022,43(1):98-104 |
| 环境暴露对健康影响的非随机化研究偏倚评价工具ROBINS-E介绍 |
| Introduction of a tool to assess Risk of Bias in Non-randomized Studies-of Environmental Exposure (ROBINS-E) |
| Received:November 12, 2020 |
| DOI：10.3760/cma.j.cn112338-20201112-01324 |
| KeyWord: 偏倚风险 评价工具 非随机化研究 环境暴露 系统综述 |
| English Key Word: Risk of bias Tool for assessment Non-randomized studies Environmental exposure Systematic review |
| FundProject:国家自然科学基金（72074011）；北京市属医院科研培育项目（PX2019071） |
| Author Name | Affiliation | E-mail | | Wang Weiwei | The National Clinical Research Center for Mental Disorders &
Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China | | | Zhou Qingxin | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Center of Evidence-based Medicine and Clinical Research, Peking University, Beijing 100191, China | | | Ma Lei | Department of Psychiatry, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China | | | Feng Shihao | School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China | | | Yang Zhirong | Primary Care Unit, School of Clinical Medicine, University of Cambridge, Cambridge CB1 8RN, UK | | | Sun Feng | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Center of Evidence-based Medicine and Clinical Research, Peking University, Beijing 100191, China | sunfeng@bjmu.edu.cn | | Zhan Siyan | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Center of Evidence-based Medicine and Clinical Research, Peking University, Beijing 100191, China
Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing 100191, China | |
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| Abstract: |
| 针对非随机化环境暴露研究Cochrane偏倚评估工具ROBINS-E的主要内容进行详细介绍，并举例说明ROBINS-E的使用方法和注意事项。ROBINS-E针对非随机化暴露研究（non-randomized studies of exposures，NRSE）的特点，设置了相应的评估领域和信号问题，为将NRSE纳入到系统综述，在GRADE框架下进行证据整合提供偏倚风险信息。 |
| English Abstract: |
| This paper summaries the Risk of Bias in Non-randomized Studies-of Environmental Exposure (ROBINS-E), a tool for evaluating risk of bias about non-randomized studies of exposures (NRSE), and introduces the application of ROBINS-E in a published NRSE. According to the characteristics of NRSE, evaluation fields and signaling questions were designed in ROBINS-E to provide essential information about risk of bias for NRSE included in systematic reviews and GRADE. ROBINS-E is the tool in assessment of risk of bias in observational studies and quasi-randomized studies. Although the tool has been used in practice to some extent, but it still needs further improvement. Attention should be paid to its update and progress. |
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