Abstract
宁宁,蔡于茂,翁榕星,王洪琳,文立章,张春来,叶健滨,陈祥生.性病相关门诊无症状就诊者生殖道沙眼衣原体感染现状及影响因素分析[J].Chinese journal of Epidemiology,2022,43(9):1436-1440
性病相关门诊无症状就诊者生殖道沙眼衣原体感染现状及影响因素分析
Chlamydia trachomatis infection and its associated factors among asymptomatic outpatients attending sexually transmitted disease-related clinics
Received:October 15, 2021  
DOI:10.3760/cma.j.cn112338-20211015-00796
KeyWord: 性传播疾病  生殖道沙眼衣原体  无症状就诊者  影响因素
English Key Word: Sexually transmitted diseases  Genital chlamydia trachomatis infection  Asymptomatic outpatients  Associated factors
FundProject:深圳市"医疗卫生三名工程"(SZSM201611077)
Author NameAffiliationE-mail
Ning Ning Department of Sexually Transmitted Disease and Leprosy Control and Prevention, Shenzhen Center for Chronic Disease Control, Shenzhen 518020, China  
Cai Yumao Department of Sexually Transmitted Disease and Leprosy Control and Prevention, Shenzhen Center for Chronic Disease Control, Shenzhen 518020, China 64165469@qq.com 
Weng Rongxing Department of Sexually Transmitted Disease and Leprosy Control and Prevention, Shenzhen Center for Chronic Disease Control, Shenzhen 518020, China  
Wang Honglin Department of Sexually Transmitted Disease and Leprosy Control and Prevention, Shenzhen Center for Chronic Disease Control, Shenzhen 518020, China  
Wen Lizhang Department of Sexually Transmitted Disease and Leprosy Control and Prevention, Shenzhen Center for Chronic Disease Control, Shenzhen 518020, China  
Zhang Chunlai Department of Sexually Transmitted Disease and Leprosy Control and Prevention, Shenzhen Center for Chronic Disease Control, Shenzhen 518020, China  
Ye Jianbin Department of Sexually Transmitted Disease and Leprosy Control and Prevention, Shenzhen Center for Chronic Disease Control, Shenzhen 518020, China  
Chen Xiangsheng National Center for Sexually Transmitted Disease Control, Chinese Center for Disease Control and Prevention, Nanjing 210042, China  
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Abstract:
      目的 了解深圳市STD相关门诊无症状就诊者生殖道沙眼衣原体(CT)感染现状及影响因素,为制定干预措施提供参考依据。方法 采用横断面调查研究方法,于2018年4月15日至5月16日在深圳市南山区、罗湖区、宝安区、龙岗区、盐田区、龙华区的22家医疗机构招募STD相关门诊就诊者,完成知情同意后,收集其社会人口学相关信息并采集尿液标本进行CT核酸检测,采用logistic回归分析CT感染的影响因素。结果 无症状就诊者CT感染率为7.16%(250/3 492)。单身(aOR=2.29,95%CI:1.65~3.16)、外地户籍(aOR=1.49,95%CI:1.04~2.13)、最近1年未检测CT(aOR=2.04,95%CI:1.03~4.05)是无症状就诊者CT感染的危险因素。外地户籍中,大专及以下文化程度占89.25%(2 176/2 438),年龄≤30岁占51.29%(1 255/2 447),≤30岁者感染CT的风险是>30岁者的1.73(95%CI:1.28~2.34)倍。结论 深圳市STD相关门诊无症状就诊者CT感染率较高,应针对性活跃年龄段、单身、文化程度较低、最近1年未检测CT的STD相关门诊就诊者开展CT常规筛查,提高重点人群对CT基本知识及不良结局的知晓率,预防不良结局的发生。
English Abstract:
      Objective To understand the prevalence of Chlamydia trachomatis (CT) infection and its associated factors among asymptomatic outpatients attending sexually transmitted disease (STD)-related clinics in Shenzhen and provide evidence for development of future interventions.Methods From April 15 to May 16,2018,a cross-sectional study was conducted and patients attending STD-related Clinics were recruited from 22 medical institutions in Nanshan,Luohu,Bao'an,Longgang,Yantian,and Longhua districts of Shenzhen.After the informed consent from each participant was obtained,social-demographic information was collected through a structured questionnaire and urine samples were collected for CT nucleic acid detection.In addition,logistic regression was used to explore associated factors of CT infection.Results In asymptomatic outpatients,the prevalence of CT infection was 7.16%(250/3 492).Being single (aOR=2.29,95%CI:1.65-3.16),without registered Shenzhen residency (aOR=1.49,95%CI:1.04-2.13),and without previous CT testing in the past year (aOR=2.04,95%CI:1.03-4.05) were the risk factors of CT infection in asymptomatic outpatients.Among participants without registered Shenzhen residency,89.25%(2 176/2 438) were college-degree or below,and 51.29%(1 255/2 447) were aged ≤ 30 years,and the risk of CT infection among those ≤ 30 years old was 1.73 times higher than those>30 years old (95%CI:1.28-2.34).Conclusions The prevalence of CT infection was high among asymptomatic outpatients attending STD-related clinics in Shenzhen.Routine CT screening should be carried out for this population,especially for those with sexually active age,being single,with low educational level,and without previous CT testing in the past year.Also,raising their awareness of knowledge and adverse outcomes of CT infection should be considered to promote routine CT screening and timely treatment.
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