| 吴洵,覃玉,苏健,陈路路,崔岚,陶然,周金意,武鸣.心血管病高危人群腰围和体重变化与血压水平变化关系的随访研究[J].Chinese journal of Epidemiology,2022,43(12):1900-1906 |
| 心血管病高危人群腰围和体重变化与血压水平变化关系的随访研究 |
| Follow-up study on the relationship between changes in waist circumference and body weight and changes in blood pressure levels among high cardiovascular risk population |
| Received:May 16, 2022 |
| DOI：10.3760/cma.j.cn112338-20220516-00419 |
| KeyWord: 心血管病 腰围 体重 血压水平 |
| English Key Word: Cardiovascular disease Waist circumference Weight Blood pressure levels |
| FundProject:国家重大公共卫生项目 |
| Author Name | Affiliation | E-mail | | Wu Xun | Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | | | Qin Yu | Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | | | Su Jian | Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | | | Chen Lulu | Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | | | Cui Lan | Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | | | Tao Ran | Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | | | Zhou Jinyi | Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | | | Wu Ming | Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | jswuming@vip.sina.com |
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| Abstract: |
| 目的 探讨心血管病高危人群中腰围和体重变化与血压水平变化的关系，为高血压及心血管病防治提供理论依据和参考。方法 选取2016年纳入随访调查的12 931名心血管病高危人群作为研究对象，将其2017-2019年长期随访数据纳入分析。统计学分析采用t检验、χ2检验和广义估计方程。结果 在心血管病高危人群中，腰围、体重和BMI增加，血压水平升高的风险高；腰围、体重和BMI减少，血压水平升高的风险低。腰围每增加1 cm，SBP增加0.200（95%CI：0.164~0.236） mmHg，DBP增加0.085（95%CI：0.066~0.105） mmHg；体重每增加1 kg，SBP增加0.355（95%CI：0.289~0.421） mmHg，DBP增加0.182（95%CI：0.144~0.220）mmHg；BMI每增加1 kg/m2，SBP增加1.100（95%CI：1.194~1.258） mmHg，DBP增加0.365（95%CI：0.273~0.456） mmHg。心血管病高危人群中农村居民相对于城市居民，SBP随腰围和体重变化更大，DBP随腰围变化更大（交互作用P<0.05）；随访高血压不患病相对于随访高血压患病人群，SBP随腰围和BMI变化更大，DBP随BMI变化更大（交互作用P<0.05）。结论 在心血管病高危人群中，腰围、体重和BMI的变化与血压水平的变化均存在正向线性相关。 |
| English Abstract: |
| Objective To investigate the relationship between changes in waist circumference, body weight, and blood pressure change in a high cardiovascular risk population and to provide a theoretical basis and reference for the prevention and treatment of hypertension and cardiovascular disease. Methods A total of 12 931 patients with a high risk of cardiovascular disease participating in the follow-up survey in 2016 were selected as the study subjects, and their long-term follow-up data from 2017 to 2019 were included in the analysis. Statistical analysis was performed using a t-test, χ2 test, and generalized estimation equation (GEE). Results Increased waist circumference, body weight, and BMI were associated with a higher risk of elevated blood pressure in people at high risk of cardiovascular disease. Waist circumference, weight, and BMI were reduced when blood pressure levels were lower. SBP and DBP increased by 0.200 (95%CI: 0.164-0.236) mmHg and 0.085 (95%CI: 0.066-0.105) mmHg for each 1 cm increase of waist circumference. SBP increased by 0.355 (95%CI: 0.289-0.421) mmHg and DBP increased by 0.182 (95%CI: 0.144-0.220) mmHg for each 1 kg increase in body weight. For each 1 kg/m2 increase in BMI, SBP increased by 1.100 (95%CI: 1.194-1.258) mmHg, and DBP increased by 0.365 (95%CI: 0.273-0.456) mmHg. Compared with urban residents, SBP changes more with waist circumference and body weight, and DBP changes more with waist circumference in high-risk cardiovascular disease groups (all P for interaction <0.05). SBP with waist circumference and BMI and DBP with BMI was greater in participants without hypertension than in those with hypertension (all P for interaction <0.05). Conclusion There is a positive linear correlation between the changes in waist circumference, body weight, and BMI and the changes in blood pressure in a high-risk cardiovascular disease population. |
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