2014-2020年青岛市急性心肌梗死发病率、死亡率特征及疾病负担分析

孙晓晖; 段海平; 余灿清; 张文忠; 张婧; 杨雪纷; 张华; 薛晓嘉; 赵园园; 张增智; 张金太; 毛丛林; 朱志刚; 王康; 马海燕; 郑晓艳; 闫泓璇; 汪韶洁; 宁锋

Abstract

孙晓晖,段海平,余灿清,张文忠,张婧,杨雪纷,张华,薛晓嘉,赵园园,张增智,张金太,毛丛林,朱志刚,王康,马海燕,郑晓艳,闫泓璇,汪韶洁,宁锋.2014-2020年青岛市急性心肌梗死发病率、死亡率特征及疾病负担分析[J].Chinese journal of Epidemiology,2023,44(2):250-256

2014-2020年青岛市急性心肌梗死发病率、死亡率特征及疾病负担分析

Analysis on incidence, mortality and disease burden of acute myocardial infarction in Qingdao, 2014-2020

Received:April 17, 2022

DOI：10.3760/cma.j.cn112338-20220825-00733

KeyWord: 急性心肌梗死发病率死亡率疾病负担平均年度变化百分比

English Key Word: Acute myocardial infarction Morbidity Mortality Burden of disease Average annual percent change

FundProject:青岛市科技惠民示范引导专项（21-1-4-rkjk-1-nsh）；青岛市优秀青年医学人才

Author Name	Affiliation	E-mail
Sun Xiaohui	Department of Chronic Non-communicable Disease Control, Qingdao Prefectural Center for Disease Prevention and Control, Qingdao 266033, China
Duan Haiping	Department of Chronic Non-communicable Disease Control, Qingdao Prefectural Center for Disease Prevention and Control, Qingdao 266033, China Department of Epidemiology and Health Biostatistics, School of Public Health, Qingdao University, Qingdao 266071, China
Yu Canqing	Department of Epidemiology and Health Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Zhang Wenzhong	Department of Cardiology, Affiliated Hospital of Qingdao University, Qingdao 266003, China
Zhang Jing	Department of Chronic Non-communicable Disease Control, Qingdao Prefectural Center for Disease Prevention and Control, Qingdao 266033, China
Yang Xuefen	Department of Chronic Non-communicable Disease Control, Qingdao Prefectural Center for Disease Prevention and Control, Qingdao 266033, China
Zhang Hua	Department of Chronic Non-communicable Disease Control, Qingdao Prefectural Center for Disease Prevention and Control, Qingdao 266033, China
Xue Xiaojia	Department of Chronic Non-communicable Disease Control, Qingdao Prefectural Center for Disease Prevention and Control, Qingdao 266033, China
Zhao Yuanyuan	Department of Chronic Non-communicable Disease Control, Qingdao Prefectural Center for Disease Prevention and Control, Qingdao 266033, China
Zhang Zengzhi	Department of Chronic Non-communicable Disease Control, Shinan Distrrict Center for Disease Control and Prevention, Qingdao 266072, China
Zhang Jintai	Department of Chronic Non-communicable Disease Control, Huangdao District Center for Disease Control and Prevention, Qingdao 266000, China
Mao Conglin	Department of Chronic Non-communicable Disease Control, Jiaozhou County Center for Disease Control and Prevention, Qingdao 266000, China
Zhu Zhigang	Department of Chronic Non-communicable Disease Control, Shibei District Center for Disease Control and Prevention, Qingdao 266012, China
Wang Kang	Department of Chronic Non-communicable Disease Control, Shibei District Center for Disease Control and Prevention, Qingdao 266012, China
Ma Haiyan	Department of Chronic Non-communicable Disease Control, Chengyang District Center for Disease Control and Prevention, Qingdao 266108, China
Zheng Xiaoyan	Department of Chronic Non-communicable Disease Control, Licang District Center for Disease Control and Prevention, Qingdao 266000, China
Yan Hongxuan	Department of Epidemiology and Health Biostatistics, School of Public Health, Qingdao University, Qingdao 266071, China
Wang Shaojie	Department of Chronic Non-communicable Disease Control, Qingdao Prefectural Center for Disease Prevention and Control, Qingdao 266033, China
Ning Feng	Department of Epidemiology and Health Biostatistics, School of Public Health, Qingdao University, Qingdao 266071, China Department of Community Health, Qingdao Prefectural Center for Disease Prevention and Control, Qingdao 266033, China	ningf1010@126.com

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Abstract:

目的描述青岛市2014-2020年急性心肌梗死（AMI）发病、死亡变化趋势以及疾病负担。方法数据来源于青岛市慢性病监测系统，采用Joinpoint对数线性回归模型估算标化发病率、死亡率平均年度变化百分比（AAPC），并计算伤残调整寿命年（DALY）评估疾病负担。结果 2014-2020年青岛市共报告AMI发病70 491例，标化发病率为54.71/10万；死亡50 832例，标化死亡率为36.55/10万。标化发病率的AAPC（95%CI）为2.86%（95%CI：0.42%~5.35%），其中男女性标化发病率AAPC（95%CI）分别为4.30%（95%CI：1.24%~7.45%）和0.78%（95%CI：-0.89%~2.47%）。Joinpoint对数回归模型分析结果显示，30~、40~岁年龄组标化发病率增长速度较快，AAPC（95%CI）分别为8.92%（95%CI：2.23%~16.06%）和6.32%（95%CI：3.30%~9.44%）；其中男性各年龄组增长趋势更为明显，30~、40~、50~岁年龄组的AAPC（95%CI）分别为11.25%（95%CI：3.54%~19.54%）、6.73%（95%CI：2.63%~10.99%）和6.72%（95%CI：2.98%~10.60%）。标化死亡率的AAPC无显著变化。DALY率由2014年的7.49/1 000上升至2020年的8.61/1 000，AAPC为1.97%（95%CI：0.36%~3.60%）。结论青岛市男性2014-2020年AMI标化发病率呈上升趋势，其中30~49岁年龄组标化发病率增长显著。AMI标化死亡率变化相对稳定。男女性疾病负担呈上升趋势。

English Abstract:

Objective To describe the characteristics and change trends of incidence, mortality and disease burden of acute myocardial infarction (AMI) in Qingdao from 2014 to 2020.Methods We analyzed the incidence data of AMI retrieved from Qingdao Chronic Diseases Surveillance System. The average annual percent change (AAPC) of morbidity and mortality of AMI were evaluated by using Joinpoint log-linear regression model. Disability adjusted life year (DALY) was used to estimate disease burden of AMI in Qingdao. Results A total of 70 491 AMI cases and 50 832 deaths of AMI occurred in Qingdao from 2014 to 2020. The age-standardized morbidity and mortality were 54.71/100 000 and 36.55/100 000, respectively. During 2014-2020, the AAPC of age-standardized morbidity was 2.86% (95%CI:0.42%-5.35%), and 4.30% (95%CI:1.24%-7.45%) in men and 0.78% (95%CI:-0.89%-2.47%) in women, respectively. The log-linear regression model showed that age-standardized morbidity in age groups 30-39, 40-49 years increased rapidly, with the AAPCs of 8.92% (95%CI:2.23%-16.06%) and 6.32% (95%CI:3.30%-9.44%), respectively. The trend was also observed in age groups 30-39, 40-49 and 50-59 years in men, with the AAPCs of 11.25% (95%CI:3.54%-19.54%), 6.73% (95%CI:2.63%-10.99%) and 6.72% (95%CI:2.98%-10.60%), respectively. There was no significant change in age-standardized mortality. The DALY rate increased from 7.49/1 000 in 2014 to 8.61/1 000 in 2020, with the AAPC of 1.97% (95%CI:0.36%-3.60%). Conclusions The age-standardized morbidity of AMI in men increased in Qingdao, especially in those aged 30-49 years, while age-standardized mortality rate of AMI was relatively stable from 2014 to 2020. The burden of disease of AMI increased in both men and women.

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