| 颜欢畅,刘裕,唐时幸,顾菁,郝元涛.HIV传播簇的风险测量及公共卫生应对研究进展[J].Chinese journal of Epidemiology,2023,44(4):677-682 |
| HIV传播簇的风险测量及公共卫生应对研究进展 |
| Progress in research on HIV cluster detection and response |
| Received:November 14, 2022 |
| DOI：10.3760/cma.j.cn112338-20221114-00969 |
| KeyWord: 艾滋病病毒 传播网络 分子网络 分子传播簇 |
| English Key Word: HIV Transmission network Molecular network Molecular transmission cluster |
| FundProject:广东省基础与应用基础研究基金（2021A1515011591）；广东省医学科学技术研究基金（A2021104） |
| Author Name | Affiliation | E-mail | | Yan Huanchang | Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China | | | Liu Yu | Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China | | | Tang Shixing | Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou 510515, China | | | Gu Jing | Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China | gujing5@mail.sysu.edu.cn | | Hao Yuantao | Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing 100191, China | haoyt@bjmu.edu.cn |
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| Abstract: |
| 开展HIV传播簇探测，及时、精准实施公共卫生应对和干预，是结束艾滋病流行的重要途径和方法。传播簇风险测量指标可分为基于传播簇既往增长的指标、基于传播簇成员特征分析的指标以及基于传播簇系统进化分析的指标三类。依据传播簇风险测量指标识别风险传播簇，将卫生服务拓展至与传播簇关联的尚未感染HIV者、既往确诊和尚未确诊的HIV感染者，可实现精准干预。本文对现有的HIV分子传播簇风险测量指标及其公共卫生应对措施进行综述，为我国艾滋病精准防控提供参考。 |
| English Abstract: |
| HIV cluster detection and response (CDR) is a critical strategy to end the HIV epidemic by offering information to identify prevention and care services gaps. The risk metrics for HIV clusters can be classified into three groups: growth-based metrics, characteristic-based metrics, and phylogeny-based metrics. When identifying HIV risk clusters, the public health response can reach people in the affected networks, including people with undiagnosed HIV, people with diagnosed HIV who might not be accessing HIV care or other services, and people without HIV who would benefit from prevention services. To provide references for HIV precise prevention in China, we summarized the risk metrics and the intervention measures for CDR. |
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