| 汪子平,景慧,滕雨芯,黄妍,Samuel Chacha,刘叶舟,张彬艳,申远,李强,米白冰,杨姣梅,颜虹,党少农.陕西省成年人群肌肉重量与生活质量的关联性研究[J].Chinese journal of Epidemiology,2023,44(6):877-884 |
| 陕西省成年人群肌肉重量与生活质量的关联性研究 |
| Association between muscle mass and quality of life in Shaanxi adults |
| Received:September 17, 2022 |
| DOI：10.3760/cma.j.cn112338-20220917-00786 |
| KeyWord: 肌肉重量 生活质量 身体功能总分 心理功能总分 |
| English Key Word: Muscle mass Quality of life Physical component summary Mental component summary |
| FundProject:陕西省自然科学基础研究计划（2021JM-034）；国家重点研发计划（2017YFC0907200，2017YFC0907201） |
| Author Name | Affiliation | E-mail | | Wang Ziping | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Jing Hui | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Teng Yuxin | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Huang Yan | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Samuel Chacha | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Liu Yezhou | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Zhang Binyan | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Shen Yuan | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Li Qiang | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Mi Baibing | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Yang Jiaomei | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Yan Hong | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | | | Dang Shaonong | Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China | tjdshn@mail.xjtu.edu.cn |
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| Abstract: |
| 目的 探讨陕西省成年人群肌肉重量与生活质量的关联性。方法 数据来源于2018-2019年建立的西北区域自然人群队列研究中陕西省人群队列的基线调查，通过健康调查12条简表测评研究对象的生活质量，包括身体功能总分（PCS）和心理功能总分（MCS），通过人体脂肪测量仪测量全身肌肉重量。采用调整混杂因素的logistic回归模型分析不同性别肌肉重量与生活质量的关系，并进行敏感性分析和亚组分析探索其稳定性，利用限制性立方样条方法探索不同性别肌肉重量与生活质量的剂量-反应关系。结果 共纳入20 595名研究对象，平均年龄55.0岁，33.4%为男性。在控制混杂因素之后，与Q1组相比，女性Q5组人群低PCS的风险下降20.6%（OR=0.794，95%CI：0.681~0.925），低MCS的风险下降20.1%（OR=0.799，95%CI：0.689~0.926）。与Q1组相比，男性Q2组人群低PCS的风险下降24.4%（OR=0.756，95%CI：0.644~0.888），但尚未发现男性肌肉重量与MCS存在显著关联。女性肌肉重量与PCS和MCS的关联呈现出显著的线性剂量-反应关系。结论 陕西省成年人群的肌肉重量与生活质量之间呈正向关联，且女性更为突出，随着肌肉重量增加，人群身体功能和心理功能不断提高。 |
| English Abstract: |
| Objective To investigate the association between muscle mass and quality of life in adults in Shaanxi adults. Methods The data in this analysis were part of the baseline survey of the Regional Ethnic Cohort Study in Northwest China from June 2018 to May 2019 in Shaanxi Province. The participants' quality of life, including physical component summary (PCS) and mental component summary (MCS), was assessed by the 12-Item Short Form Survey, and the Body Fat Determination System measured muscle mass. A logistic regression model with adjustment for confounding factors was established to analyze the association between muscle mass and quality of life in different genders. Further, sensitivity and subgroup analyses were conducted to explore its stability. Finally, a restricted cubic spline was employed to investigate the dose-response relationship between muscle mass and quality of life in different genders. Results A total of 20 595 participants were included, with an average age of 55.0, and 33.4% were male. After controlling for potential confounders, compared with the Q1 group, the risk of low PCS was reduced by 20.6% (OR=0.794, 95%CI: 0.681-0.925) and the risk of low MCS was lower reduced by 20.1% (OR=0.799, 95%CI: 0.689-0.926) in female Q5 groups. Compared with the Q1 group, the risk of low PCS was reduced by 24.4% (OR=0.756, 95%CI: 0.644-0.888) in the male Q2 group. However, no significant association between muscle mass and MCS in males has been found. In females, restricted cubic spline analysis showed a significant linear dose-response relationship between muscle mass and PCS and MCS.Conclusions There is a positive association between muscle mass and quality of life in Shaanxi adults, especially females. With the increase in muscle mass, the physical and mental functions of the population continue to improve. |
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