张克春,孟晓军,胡甜,罗丹,曹赫,林启辉,邹华春.抗病毒治疗男男性行为人群HIV感染者对“检测不到等于无传染性”理念的认知调查[J].Chinese journal of Epidemiology,2023,44(10):1610-1615 |
抗病毒治疗男男性行为人群HIV感染者对“检测不到等于无传染性”理念的认知调查 |
Survey on the cognition of the “undetectable equals untransmittable” concept among HIV-infected men who have sex with men receiving antiviral treatment |
Received:April 24, 2023 |
DOI:10.3760/cma.j.cn112338-20230424-00264 |
KeyWord: 艾滋病病毒 男男性行为人群 病毒载量 认知 |
English Key Word: HIV Men who have sex with men Viral load Cognition |
FundProject:深圳市龙华区引进高层次医学团队项目(HLPM201907020105);国家自然科学基金优秀青年项目(82022064);无锡市科技局项目(Y20222006) |
Author Name | Affiliation | E-mail | Zhang Kechun | Longhua District Centre for Disease Control and Prevention, Shenzhen 518109, China | | Meng Xiaojun | Wuxi Prefectural Centre for Disease Control and Prevention, Wuxi 214023, China | | Hu Tian | Longhua District Centre for Disease Control and Prevention, Shenzhen 518109, China | | Luo Dan | School of Public Health(Shenzhen), Sun Yat-sen University, Shenzhen 518107, China | | Cao He | Longhua District Centre for Disease Control and Prevention, Shenzhen 518109, China | | Lin Qihui | Longhua District Centre for Disease Control and Prevention, Shenzhen 518109, China | | Zou Huachun | School of Public Health(Shenzhen), Sun Yat-sen University, Shenzhen 518107, China | zouhuachun@mail.sysu.edu.cn |
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Abstract: |
目的 了解深圳市抗病毒治疗MSM HIV感染者(MSM感染者)对“检测不到等于无传染性”(“U=U”)理念的认知状况,并分析影响其认知的因素,为制定针对该理念的宣传和倡导策略提供依据。方法 结合HIV感染者日常随访,在深圳市通过方便抽样招募抗病毒治疗MSM感染者为研究对象,开展横断面调查,估算样本量为475例。利用调查问卷收集研究对象的社会人口学、性行为、抗病毒治疗、病毒载量检测信息,以及对“U=U”理念的认知情况等内容,并采用logistic回归模型分析影响研究对象接受“U=U”理念的相关因素。结果 共490例抗病毒治疗MSM感染者,其中知晓“U=U”理念的占60.2%(295/490),接受“U=U”理念的占50.6%(248/490)。多因素logistic回归分析结果显示,大专及以上文化程度(aOR=1.76,95%CI:1.12~2.75)的研究对象更可能接受“U=U”理念;无本地户籍(aOR=0.51,95%CI:0.29~0.92)、最近1次病毒载量检测结果>0拷贝数/ml(aOR=0.61,95%CI:0.38~0.98)和不知晓“U=U”理念(aOR=0.13,95%CI:0.09~0.21)的研究对象更可能不接受“U=U”理念。结论 深圳市抗病毒治疗MSM感染者对“U=U”理念的认知仍处于较低水平,应结合其日常随访,通过医务人员加大对该理念的宣传和倡导力度,提高MSM感染者抗病毒治疗的依从性和治疗的效果。同时,要根据MSM感染者的人群特点,制定相关工作指南,提高“U=U”理念宣传和倡导工作的规范性。 |
English Abstract: |
Objective To explore the cognition of the "undetectable equals untransmittable" ("U=U") concept and associated factors among HIV-infected men who have sex with men (MSM) receiving antiviral treatment (ART) in Shenzhen, and provide evidence for designing promotion and advocacy strategies for the "U=U" concept. Methods We recruited HIV-infected MSM receiving ART using convenient sampling method combined with routine follow-up in Shenzhen through conducting observational survey. The sample size was estimated to be 475. A questionnaire was administered to collect socio-demographic characteristics, sexual behaviors, ART, viral load testing and the cognition towards "U=U" in HIV-infected MSM. Logistic regression was used to access factors associated with acceptance of "U=U". Results A total of 490 HIV-infected MSM receiving ART were recruited. Of whom, 60.2% (295/490) were aware of "U=U" and 50.6% (248/490) accepted "U=U". Multiple logistic regression showed that participants who had an educational level of college or above (aOR=1.76,95%CI: 1.12-2.75) were more likely to accept "U=U". Those who had no local residency (aOR=0.51,95%CI: 0.29-0.92), had viral load >0 copies/ml in the last testing (aOR=0.61,95%CI: 0.38-0.98) and were unaware of "U=U" (aOR=0.13, 95%CI: 0.09-0.21), were less likely to accept "U=U". Conclusions HIV-infected MSM receiving ART had a low cognition level of "U=U" in Shenzhen. Promotion and advocacy on this concept through healthcare workers should be enhanced in combination with routine follow-up in order to improve their ART adherence and outcome of treatment. Furthermore, developing related guidelines on "U=U" according to the characteristics of HIV-infected individuals is warranted to improve the normalization of promotion and advocacy on "U=U". |
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