Abstract
王旭,谢今朝,龙志聪,李菁华,郝元涛,揭育胜,顾菁.常见代谢相关共病对慢性乙型肝炎患者健康结局的影响及管理策略研究进展[J].Chinese journal of Epidemiology,2024,45(2):319-324
常见代谢相关共病对慢性乙型肝炎患者健康结局的影响及管理策略研究进展
Research progress on the effect of common metabolism-related comorbidities on health outcomes and management strategies in patients with chronic hepatitis B
Received:May 18, 2023  
DOI:10.3760/cma.j.cn112338-20230518-00309
KeyWord: 慢性乙型肝炎  慢性非传染性疾病  共病  共病管理
English Key Word: Chronic hepatitis B  Chronic non-communicable diseases  Comorbidities  Comorbidity management
FundProject:国家科技重大专项(2018ZX10715004)
Author NameAffiliationE-mail
Wang Xu Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China  
Xie Jinzhao Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China  
Long Zhicong Department of Infectious Diseases, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China  
Li Jinghua Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China  
Hao Yuantao Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China
Center of Global Health Research, Sun Yat-sen University, Guangzhou 510080, China
Center for Health Information Research, Sun Yat-sen University, Guangzhou 510300, China
Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing 100191, China 
 
Jie Yusheng Department of Infectious Diseases, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China jieyush@mail.sysu.edu.cn 
Gu Jing Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China
Center of Global Health Research, Sun Yat-sen University, Guangzhou 510080, China
Center for Health Information Research, Sun Yat-sen University, Guangzhou 510300, China 
gujing5@mail.sysu.edu.cn 
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Abstract:
      随着慢性乙型肝炎(CHB)患者期望寿命的延长和生活方式的改变,慢性非传染性疾病(NCDs)共病在CHB患者疾病进展和健康预后的重要性逐渐增加。本文对CHB和NCDs共病相关研究进行综述,探讨了共患如MS、糖尿病等常见代谢相关疾病对CHB患者健康结局的影响,总结了目前CHB共病管理的研究现状并提出了相关建议,为未来明确CHB患者共病的临床特征和流行趋势,降低CHB共病患者疾病负担,建立系统性共病联合管理体系提供依据。
English Abstract:
      With the increasing life expectancy and lifestyle changes of patients with chronic hepatitis B (CHB), the significance of comorbidities of chronic non-communicable diseases (NCDs) in disease progression and health prognosis of CHB patients is gaining prominence. This study aims to explore the association between CHB and NCDs comorbidities, focusing on the impact of common metabolism-related diseases, such as metabolic syndrome and diabetes, on the health outcomes of CHB patients. We also summarize studies on integrating the management of comorbidities in CHB patients and provide relevant recommendations for effective management. The findings of this study serve as a foundation for understanding the clinical characteristics and prevalence trends, reducing the disease burden of comorbidities among CHB patients, and establishing a comprehensive and coordinated management system for comorbidities.
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