| 蒋颖,何威,杨菲,石钰炜,王文杰,舒强,唐金陵,朱善宽.出生队列及其在中国的现状与展望[J].Chinese journal of Epidemiology,2024,45(12):1745-1750 |
| 出生队列及其在中国的现状与展望 |
| Birth cohorts and their current status and prospects in China |
| Received:August 14, 2024 |
| DOI：10.3760/cma.j.cn112338-20240814-00503 |
| KeyWord: 队列 出生队列 队列研究 流行病学 妇幼健康 |
| English Key Word: Cohort Birth cohort Cohort study Epidemiology Maternal and child health |
| FundProject:国家重点研发计划(2022YFC2705300) |
| Author Name | Affiliation | E-mail | | Jiang Ying | School of Public Health, Zhejiang University, Hangzhou 310000, China | | | He Wei | School of Public Health, Zhejiang University, Hangzhou 310000, China
Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310000, China | | | Yang Fei | School of Public Health, Zhejiang University, Hangzhou 310000, China
Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310000, China | | | Shi Yuwei | School of Public Health, Zhejiang University, Hangzhou 310000, China
Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310000, China | | | Wang Wenjie | School of Public Health, Zhejiang University, Hangzhou 310000, China
Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310000, China | | | Shu Qiang | Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310000, China
Binjiang Institute of Zhejiang University, Hangzhou 310000, China | | | Tang Jinling | Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310000, China
Faculty of Computer Science and Control Engineering, Shenzhen University of Advanced Technology, Shenzhen 518000, China
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518000, China | jltang@siat.ac.cn | | Zhu Shankuan | School of Public Health, Zhejiang University, Hangzhou 310000, China
Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310000, China
Binjiang Institute of Zhejiang University, Hangzhou 310000, China | zsk@zju.edu.cn |
|
| Hits: 254 |
| Download times: 131 |
| Abstract: |
| 在我国婚育年龄推迟、生育意愿下降、人口老龄化的形势下，妇幼健康与优生优育已成为重要且紧迫的问题。出生队列作为研究妇幼健康的重要公共平台已凸显其重要性。在过去20年里，我国主要城市和地区建立了几十个出生队列，队列大小从几千例到几十万例不等，尤其后期建立的大型队列，收集的信息十分广泛，采集了母亲和子代各种生物样本，也取得了初步的成果。但是，我国的出生队列建设还存在诸多问题和挑战，主要体现在：中、小型队列缺乏明确的研究主题；在强调健康生物决定因素的同时，对行为和社会决定因素认识和重视不够充分；收集的变量数目和数据质量参差不齐，不同队列数据合并和共享存在困难；长期随访存在明显的困难和不足；长期维持的资源存在很大的不确定性，等。因此，笔者认为成功的出生队列应围绕国家妇幼健康紧迫的重大问题，积极争取国家和社会的重视和支持，在做好专业工作之外，还需做好克制、忍耐、坚持、奉献、合作的精神准备。 |
| English Abstract: |
| In the context of delayed marriage and parenthood, decreased willingness in having children, and population aging in China, maternal and child health has become an important and urgent issue. Being essential platforms for research in maternal and child health, the importance of birth cohorts has been widely recognized. In the past 20 years, tens of birth cohorts have been established in major cities and regions of China, with cohorts ranging from thousands to hundreds of thousands. These cohorts, particularly those large ones launched in recent years, have collected a wide spectrum of data and biological samples from mothers and children. Although they have made considerable preliminary achievements, there remain difficulties and challenges. The significant challenges include small and medium-sized cohorts' lacking of clear research themes; insufficient recognition of and emphasis on behavioral and social determinants of health while emphasizing biological determinants of health; variations in types of variables and quality of data collected, which make it difficult for cohorts to be merged and shared; lack of and difficulties in long-term follow-up; significant uncertainties in resources for long-term sustention of the cohorts, and so on. So, we argue that birth cohorts should focus on essential and urgent issues in maternal and child health in the country and seek recognition and support from the government and the entire society. Last but not least, the overall success of birth cohorts in the country requires scientists to be not only academically capable, but also realistic, persistent, altruistic, and collaborative. |
|
View Fulltext
Html FullText
View/Add Comment Download reader |
| Close |
|
|
|