| 赵惠霖,林普生,谢韶英,赵茜茜,陈焕辉,刘家忠,曾志忠,王锐航.从重点监测地区看在广东省消灭脊髓灰质炎的前景[J].Chinese journal of Epidemiology,1985,6(4):236-238 |
| 从重点监测地区看在广东省消灭脊髓灰质炎的前景 |
| Exploring the Prospect of Eradicating Poliomyelitis from Guang-dong Province basing on Data from the focal point Surveillance Area |
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| Abstract: |
| 调查材料表明,通过大规模的服食糖丸疫苗,脊灰炎流行已在广东得到控制。其流行病学表现亦有恨大改变;在计划免疫好地区的儿童粪便及污水检材中均未能检出脊灰炎病毒;82.1%~96.8%的人有I~Ⅱ型脊灰炎抗体;97.7%及90%的产妇及脐血三个型脊灰炎抗体阳性;说明这些地区人群内的传播链已濒中断。但野毒株仍可在预防接种不良地区检出,并存在着免疫裂隙,故爆发的危险依然存在,必须进一步加强服苗工作。 |
| English Abstract: |
The statistical data of paralytic poliomyelitis from Guang-dong province in 1956-1983 showed epidemic poliomyelitis has been brought under control, and its epidemiologic features had been greatly changed during the past 28 years. This may be related to the use of live attenuated polio-vaccine Since 1964.
A survey conducted in 1982-1983 showed that any type of poliovirus could not be isolated from 258 cases of pre-school aged children and 83 sewage samples in the population of wellimmunized areas, 82.1-96.8% residents have had type 1-3 poliovirus neutralizing antibody, and 30 maternal and umbilical cord blood samples were triple antibody positive in 97.7%and 90% samples respectively. The results suggested that probably interruption of the chain of paralytic Polioviruses was nearly achieved in the well-immunized population.
However,a number of virulent poliovirus strains can still be isolated from the poorly vaccinated communities, so that it may be possible for a virus to spread through a population and some other outbreaks may be expected. |
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