| 山东省部分地区脊髓灰质炎监测与控制协作组.山东省临朐、禹城两县儿童脊髓灰质炎中和抗体水平调查[J].Chinese journal of Epidemiology,1991,12(3):146-149 |
| 山东省临朐、禹城两县儿童脊髓灰质炎中和抗体水平调查 |
| A Seroepidemiological Survey of Neutralization Antibodies to Polioviruses in Linqu and Yucheng Counties of Shandong Province, China |
| Received:March 05, 1990 Revised:March 25, 1990 |
| DOI： |
| KeyWord: 脊髓灰质炎病毒 中和抗体 |
| English Key Word: Polioviruses Neutralization Antibodies |
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| Abstract: |
| 本文以微量中和试验共检测501份血清标本。结果表明:临朐县儿童脊灰Ⅰ、Ⅱ、Ⅲ型中和抗体之阳性率和几何平均滴度(GMT)分别为82.54%、80.56%、82.94%和27.06、22.94、24.24,禹城县则分别为84.34%、51.81%、59.04%和16.78、2.79、3.40,除Ⅰ型抗体阳性率外,其余各项临朐县均高于禹城县(P<0.01);上述指标在2~4岁年龄组最高,而不同性别、不同乡(镇)儿童之间无显著性差异(P>0.05)。结果提示,开展计划免疫有利于改善儿童免疫状况,今后仍需提高TOPV接种率及接种质量。 |
| English Abstract: |
| Two hundred and fifty two serum samples from Linqu county and 249 serum samples from Yucheng county, in Shandong province, China, were collected among the age group of 0~, 1~, 2~, 3~ and 5~9 years old and assayed by microneutralization test in 1989. The results showed that the positive rates (PRs) and geometric mean titres (GMTs) of antibodies to poliovirus type 1~3 in Linqu county were 82.54%、80.56%、82.94% and 27.06、22.94、24.24, respectively, and much significantly higher than those, in Yucheng county(84.34%、51.81%、59.04% and 16.78、2.79、3.40) except the PR to type1. for children in both counties, the PRs and GMTs were highest in the age group of 2~4 years old, and no significant difference was found between male and female. All above indicated that EPI was helpful for improving immune status of children, the coverage of TOPV and quality of vaccination should still be emphasized in future EPI works. |
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