陈惠峰,郭志宏,顾云忠,张友金,陈桂尧,杨介者,姜霞玲,沈月根,陶志华,王文刚,姚军,钱本立.新生儿乙肝疫苗第2针接种时间与免疫效果关系研究[J].Chinese journal of Epidemiology,1994,15(6):349-350 |
新生儿乙肝疫苗第2针接种时间与免疫效果关系研究 |
A Study on Relation Between Effect of HB Vaccination and Time of the Second Injection |
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DOI: |
KeyWord: 乙肝疫苗 接种时间 |
English Key Word: Hepatitis B vaccine Protective rate |
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Abstract: |
新生儿乙肝疫苗免疫接种首针“0”和第3针“6”保持不变,将第2针分为30、40、50、60天组,于第2针免后和全程免后1个月各采血检测,各组抗—HBs阳转率和滴度均无组间差异。不论HBsAg阴性和HBsAg阳性母亲组的新生儿抗—HBs消长变化均与0、1、6程序结果相似。提示对山区、海岛等受客观条件影响大的地区,新生儿乙肝疫苗第2针接种时间可在30~60天完成。 |
English Abstract: |
Three kinds of hepatitis B vaccination schedule in neonates were compared. The schedule included 0, 40 day, 6 month; 0, 50 day, 6 month; 0, 60 day. 6 month; and was controlled by the 0, 30 day, 6 month schedule. The results showed that there was no statistically significant difference among three kinds of schedule, no matter who were neonates of HBs Ag-positive mother or neonates of HBsAg-negative mother. These indicated that in areas with poor condition, such as mountain, island, the second injection of hepatitis B vaccine in neonates may be completed within 30-60 days. |
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