| 倪进发,阚晓宏,毕鹏,孙业桓,章秋霞,张庶民,程慧,黄守凯.丙型肝炎病毒感染后慢性转化率的流行病学研究[J].Chinese journal of Epidemiology,1998,19(3):144-146 |
| 丙型肝炎病毒感染后慢性转化率的流行病学研究 |
| An Epidemiological Study on the Rate of Becoming Chronic in HCV Infection |
| Received:October 31, 1997 Revised:December 10, 1997 |
| DOI： |
| KeyWord: 丙型肝炎 慢性转化率 |
| English Key Word: Hepatitis C Chronic rate |
| FundProject:安徽省自然科学基金 |
| Author Name | Affiliation | | Ni Jinfa | Department of Epidemiology, Anhui Medical University, Hefei 230032 | | Kan Xiaohong | Department of Epidemiology, Anhui Medical University, Hefei 230032 | | Bi Peng | Department of Epidemiology, Anhui Medical University, Hefei 230032 | | Sun Yeheng | Department of Epidemiology, Anhui Medical University, Hefei 230032 | | Zhang Qiuxia | 安徽省立医院传染科 | | Zhang Shumin | 中国药品生物制品检定所疫苗二室 | | Cheng Hui | Department of Epidemiology, Anhui Medical University, Hefei 230032 | | Huang Shoukai | Department of Epidemiology, Anhui Medical University, Hefei 230032 |
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| Abstract: |
| 笔者选择1992～1996年间，安徽某乡“职业”供血员和2所省级医院住院病人中，抗-HCV(+)和/或HCV RNA(+)者为调查对象。追访了他们HCV感染及其后的有关重要临床诊治和流行病学信息，同时调查了感染者的现况及相关实验室指标检测，描述了供血员人群丙型肝炎病毒感染后慢性转化率变化趋势。结果HCV感染6个月后慢性转化率为55.93%，1～4年慢性转化率依次为50%、48.54%、46.47%和46.43%。表明其感染后慢性转化率一直持续高水平，下降缓慢，尤其2年后基本稳定在46%～48%，远高于乙型肝炎5%～10%的慢性转化率。 |
| English Abstract: |
| Anti-HCV(+) and/or HCV RNA(+) were chosen for study on patients admitted to two provincial hospitals and “professional” blood donors in one of the areas in Anhui province in 1992-1996.Clinical diagnosis,treatment and epidemiology on HCV infection were retrospectively reviewed and in the meantime their present condition together with experimental data were studied;Chronic tendency on HCV infection of blood donors was described.Results showed that the rates of duration on becoming chronic for HCV infection were:six month later-55.93%,one year-50%,two-years-48.54%,three years-46.47% and four years-46.43%.Rate of becoming chronic after HCV infection was continuously in high level,then slowly decreasing, to 46%-48% in two years,still much higher than hepatitis B which had a rate of 5%-10% becoming chronic. |
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