朱彪,吴南屏,强来英,邵一鸣.人类免疫缺陷病毒血源传播问题的探讨[J].Chinese journal of Epidemiology,2000,21(2):140-142 |
人类免疫缺陷病毒血源传播问题的探讨 |
The serologic study on the blood transmission origin of HIV |
Received:August 29, 1999 |
DOI: |
KeyWord: 人类免疫缺陷病毒 乙型肝炎病毒 丙型肝炎病毒 血源传播 |
English Key Word: HIV HBV HCV Blood spread |
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Abstract: |
目的 探讨人类免疫缺陷病毒 (HIV)血源传播来源问题. 方法 收集全国各地HIV阳性血清 6 2份, 其中献血员血清 2 7份, 静脉吸毒者血清35份, 用EIA法进行HBV、HCV血清学检测. 结果 HIV感染者HBV总感染率为 53. 2%(33/62) 抗 -HCV阳性率为95. 2% (59/62). HIV、HBV、HCV三重感染率为51. 6% (32/62), HIV、HCV和HIV、HBV二重感染率分别为27. 4%(17/62)和1. 6%(1/62). 献血员中HBV总感染率44. 4%(12/27), 抗 -HCV阳性率 10 0 % (27/27) 静脉吸毒者中HBV总感染率60. 0%(21/35), 抗 -HCV阳性率91. 4%(32/35). 经统计学处理, 两人群HBV感染率与抗 -HCV阳性率差异无显著性 (P>0. 05). 对两人群中HIV、HBV、HCV三重、双重、单一感染率分析发现, 两人群间差异也无显著性 (P>0. 05). 结论 结果提示, HIV感染献血员和HIV感染静脉吸毒者HCV感染率很高 两人群在感染HIV、HBV、HCV高危因素上存在着一定的内在联系, 静脉吸毒可能是引起我国HIV血源传播的主要根源 |
English Abstract: |
Objective To study the origin of HIV blood spread in China. Methods Markers of HBV and HCV in 62 HIV-infections sera (27 blood donors and 35 i. v. drug users) were detected by EIA. Results The Results show that the total HBV infection was 53. 2%(33/62) and anti-HCV positive 95. 2 %(59/62). Super-infection of HIV、HBV、HCV was 51. 6%(32/60) and super-infection of HIV、HCV and HIV、HBV were 27. 4 %(17/62) and 1. 6 %(1/62). Comparing the markers of HBV and anti-HCV between blood donors and i. v. drug users, there was no statistical significant difference( P 0. 05 ). The super- infection of HIV、HBV、HCV and HIV、HCV and HIV、HBV were also no statistical differences ( P 0. 05 ) between two groups. Conclusion Resnlts indicated that a common infection mechanism might exist between Chinese HIV- infection blood donors and i. v. drug users. |
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