张之伦,朱向军,丁亚兴,解晓华,高志刚,李永成,张颖,夏卫东,刘勇.天津市甲型肝炎免疫预防控制措施效果评价[J].Chinese journal of Epidemiology,2007,28(10):1000-1003 |
天津市甲型肝炎免疫预防控制措施效果评价 |
Evaluation an the role of hepatitis A vaccine in the prevention and control of hepatitis A in Tianjin city |
Received:May 24, 2007 |
DOI: |
KeyWord: 甲型肝炎疫苗 免疫预防 效果评价 |
English Key Word: Hepatitis A vaccine Immune prevention Evaluation of effectiveness |
FundProject: |
Author Name | Affiliation | Zhang Zhilun | Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China | Zhu Xiangjun | Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China | Ding Yaxing | Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China | Xie Xiaohua | Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China | Gao Zhigang | Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China | Li Yongcheng | Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China | Zhang Ying | Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China | Xia Weidong | Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China | Liu Yong | Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China |
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Abstract: |
目的 评价天津啊实施甲型肝炎(甲肝)免疫策略后控制甲肝的效果。方法 分析天津1990—2006年甲肝疫情资料,评价疫情报告系统,估算甲肝疫苗目标人群接种率,对比1999年和2005年15岁以下健康人群甲肝抗体水平。结果 天津市甲肝发病率从1990年的25.26/10万降到2006年的0.82/10万,甲肝在病毒性肝炎中的比例从1990年的30.43%降到2006年的1.05%;估算全市目标人群甲肝疫苗接种率平均为72.7%;2005年15岁以下人群甲月r抗体阳性串达到61.84%,明显高于1999年的29.90%。结论 天津市5年甲肝疫苗免疫策略的实践成功控制了甲肝流行。 |
English Abstract: |
Objective To evaluate the effects of prevention and control strategies on hepatitis A.Methods Surveillance data on hepatitis A from 1990 to 2006 in Tianjin was analyzed,and the coverage rate of hepatitis A vaccine among targeted population was estimated,to campare the anti-HAV IgG level of children younger than 15 years old in 1999 and in 2005.Results showed that a) the morbidity of hepatitis A decreased from 25.26/105 in 1990 to 0.82/105 in 2006;b) the ratio of hepatitis A in viral hepatitis decreased from 30.43'16 in 1991 to 1.05% in 2006;c) the estimated coverage rate was 72.7%;d) the positive rate of anti-HAV among children younger than 15 years old in 2005 was distinctly higher than that in 1999.Conclusion Positive results showed that it was successful to use hepatitis A vaccine as the strategy to prevent and control hepatitis A in the past five years in Tianjin. |
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