朱智勇,姚苹苹,陆群英,翁景清,朱函坪,李岩金,徐芳,李敏红,傅桂明,赵芝雅.肾综合征出血热疫苗的纯化与人体观察[J].Chinese journal of Epidemiology,2008,29(10):1056 |
肾综合征出血热疫苗的纯化与人体观察 |
Purification and observation of inactivated hemorrhagic fever with renal syndrome vaccine in human |
Received:March 05, 2008 |
DOI: |
KeyWord: 肾综合征出血热疫苗 纯化 人体观察 |
English Key Word: Hemorrhagic fever with renal syndrome vaccine Purification Human observe |
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Author Name | Affiliation | ZHU Zhi-yong | Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China | YAO Ping-ping | Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China | LU Qun-ying | Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China | WENG Jing-qing | Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China | ZHU Han-ping | Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China | LI Yan-jin | Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China | XU Fang | Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China | LI Min-hong | Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China | FU Gui-ming | Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China | ZHAO Zhi-ya | Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China |
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Abstract: |
肾综合征出血热(HFRS)足由汉滩病毒引起的急性传染病,世界各地均有发生.用长爪沙鼠肾原代细胞培养HFRS病毒,经β-丙内脂灭活病毒,研制成功汉坦型、汉城型及汉坦型加汉城型三种疫苗,已取得很好的预防效果[1,2].为使产品的质量进一步提高,进行了疫苗纯化的研究. |
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