Abstract
尚肖肖,王志萍,赵仲堂.维生素B12在神经管缺陷一级预防中的作用研究进展[J].Chinese journal of Epidemiology,2010,31(5):579-583
维生素B12在神经管缺陷一级预防中的作用研究进展
Progress on the role of vitamin B12 in primary prevention of neural tube defects
Received:October 31, 2009  
DOI:10.3760/cma.j.issn.0254-6450.2010.05.025
KeyWord: 维生素B12  神经管缺陷  一级预防
English Key Word: Vitamin B  Neural tube defects  Primary prevention
FundProject:“十一五”国家科技支撑计划(2006BAl05A01)
Author NameAffiliationE-mail
SHANG Xiao-xiao Departmena of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China  
WANG Zhi-ping Departmena of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China zhipingw@sdu.edu.Cn 
ZHAO Zhong-tang Departmena of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China  
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Abstract:
      维生素B12(Vit B12)又称钴胺素(cobalamins),是一组有钴结合咕啉环的红色类咕啉化合物的总称,是一种维持人体正常代谢和机能不可缺少的、机体不能合成的微量营养素。自1980年Schorah等报道低水平Vit B12和脑畸形发生有关后,Vit B12 与神经管缺陷(neural tube defects,NTDs)的关系引起广泛关注。
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