尚肖肖,王志萍,赵仲堂.维生素B12在神经管缺陷一级预防中的作用研究进展[J].Chinese journal of Epidemiology,2010,31(5):579-583 |
维生素B12在神经管缺陷一级预防中的作用研究进展 |
Progress on the role of vitamin B12 in primary prevention of neural tube defects |
Received:October 31, 2009 |
DOI:10.3760/cma.j.issn.0254-6450.2010.05.025 |
KeyWord: 维生素B12 神经管缺陷 一级预防 |
English Key Word: Vitamin B Neural tube defects Primary prevention |
FundProject:“十一五”国家科技支撑计划(2006BAl05A01) |
Author Name | Affiliation | E-mail | SHANG Xiao-xiao | Departmena of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China | | WANG Zhi-ping | Departmena of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China | zhipingw@sdu.edu.Cn | ZHAO Zhong-tang | Departmena of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China | |
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Abstract: |
维生素B12(Vit B12)又称钴胺素(cobalamins),是一组有钴结合咕啉环的红色类咕啉化合物的总称,是一种维持人体正常代谢和机能不可缺少的、机体不能合成的微量营养素。自1980年Schorah等报道低水平Vit B12和脑畸形发生有关后,Vit B12 与神经管缺陷(neural tube defects,NTDs)的关系引起广泛关注。 |
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